In recent years, the field of stem cell and developmental biology has seen remarkable breakthroughs that have deepened our understanding of how organisms grow, age and regenerate, with major ...

From the generation of embryo-like structures to the establishment of cell-based approaches to model or treat disease, the field of stem cell and developmental biology has impressively progressed ...

Descriptions of the embryo go back at least to the time of Aristotle, but it has only been since the late 19 th century and early 20 th century that advances in experimental approaches allowed ...

Human pluripotent stem-cells (HPSCs)—including human embryonic stem-cells and human induced pluripotent stem-cells—are reshaping the landscape of regenerative medicine.1,2 In Parkinson's disease, ...

Stem cells can self-renew and differentiate into a wide variety of cell types, making them critical components in embryonic development. In adults, stem cell populations, such as those in the ...

Retinoic acid, the active state of Vitamin A, appears to regulate how stem cells enter and exit a transient state central to their role in wound repair. Retinoic acid, the active state of Vitamin A, ...

A discovery may boost the effectiveness of stem-cell transplants, commonly used for patients with cancer, blood disorders, or autoimmune diseases caused by defective stem cells, which produce all the ...