Proteins and peptides form the cornerstone of cellular function, serving not only as essential catalysts and structural components but also as mediators of signalling and regulation in health and ...

Findings from preclinical studies could point to therapeutic strategies for Huntington’s disease, as well as other neurodegenerative disorders and potentially cancer.

An illustration of one of Grove Biopharma’s protein-like polymers in sky blue and bright yellow. These protein-like polymers may help target intractable cancer-causing proteins. Credit: Saeed Najafi, ...

Cells rely on tiny molecules called microRNAs to tune which genes are active and when. Cells must carefully control the lifespan of microRNAs to prevent widespread disruption to gene regulation. A new ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

Disulphide bonds play a critical role in stabilising the three‐dimensional structures of proteins and ensuring their correct function. Their precise mapping is essential not only for understanding ...

Biotech advances from UT’s new Deep Proteins group are changing the game with help from artificial intelligence. Researchers study the three dimensional structures of molecules on a wall-sized video ...

Nonsense-mediated mRNA decay (NMD) is one of the most important processes in our cells to ensure that no faulty or incomplete proteins are produced. Scientists have now identified a central mechanism ...

A new type of blood test that analyses the folding of amino acids rather than their amounts may detect earliest biological signs of Alzheimer's disease, according to a study. Analysis of blood plasma ...

A team at UT Southwestern Medical Center has identified a structural trick that lets viruses translate their genetic code inside human cells, even when that code is riddled with “bad” codons the host ...

An international research team led by Konrad Meister from Boise State University’s Department of Chemistry and Biochemistry and the Max Planck Institute for Polymer Research has identified a new class ...

Saint Louis University’s Protein Core is a shared-use core facility that supports expression, purification and analysis of reagent and preclinical proteins. The core provides instrumentation and ...