“Start low, go slow.” Geriatric pharmacology texts and recent systematic reviews (e.g., on dosing of oncology drugs) warn ...

A new combination of existing drugs reduces the size of cancerous tumors much more effectively than current treatments. A new drug lead shows promise that it could reduce the size of cancerous tumors ...

One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others ...

The application of pharmacogenetics in identifying single nucleotide polymorphisms (SNPs) in DNA sequences that cause clinically significant alterations in drug-metabolizing enzyme activities is ...

This article is based on a poster originally authored by Daniel A. Barr, Mario Öeren, Peter A. Hunt, Jonathan D. Tyzack, Tomáš Chrien, Tamsin E. Mansley and Matthew D. Segall, which was presented at ...

The golden years should bring freedom from health worries, yet millions of seniors find their diabetes medications becoming less effective or causing dangerous side effects as they age. What worked ...

The human liver plays a pivotal role in drug metabolism, largely attributable to the diverse family of UDP-glucuronosyltransferases (UGTs) that catalyse glucuronidation reactions. This conjugation ...

One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others.

Drugs like Wegovy and Zepbound have been hailed as miracle treatments. But one in 10 people are what scientists call ...

Often labeled a “natural Ozempic,” berberine is widely discussed as a metabolic aid. Yet research suggests its influence may ...

GLP-1 medications have transformed obesity treatment and renewed attention on the science behind medical weight loss. But health experts say one important truth remains: medication alone isn’t ...