Researchers found three master genes that alter brain development in Down syndrome, offering new clues about learning and memory differences.

Researchers identified three chromosome 21 genes that are overactive in brain cells of individuals with Down syndrome, and demonstrated partial molecular correction using antisense oligonucleotides.

A research team led by scientists at Queen Mary University of London and University College London (UCL) has found new clues about how the brains of people with Down syndrome develop differently from ...

Scientists from Duke-NUS Medical School, working with collaborators at Imperial College London and partners in Europe and the United States, have uncovered new insights into how an additional copy of ...

Mosaic Down syndrome has some cells with three copies of chromosome 21, and some with two instead of all three. Only about 1% to 2% of people with Down syndrome have mosaic Down syndrome. The severity ...

Decades ago, researchers showed that Down syndrome (also known as trisomy 21), was caused when individuals carried an extra copy of chromosome 21. Down syndrome is also the most common genetic cause ...

People with Down's syndrome face a higher risk of developing Leukemia. Now researchers from the University of Copenhagen and Stanford University explain why, by identifying specific changes in blood ...

The study links genetic and regulatory changes to increased erythrocyte production and leukemia risk while also identifying oxidative stress as a key factor in these abnormalities. Study: Single-cell ...

Human karyotype of Down syndrome. Autosomal abnormalities. Trisomy 21. [Rujirat Boonyong/Getty Images] Faulty brain circuits seen in Down syndrome may be caused by the lack of a particular molecule ...

Last month, San Diego-based biotech company Sequenom released its long-awaited early pregnancy test for Down syndrome. Unlike previous methods such as amniocentesis, which carries a significant risk ...