(PHILADELPHIA) – Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that ...

Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant ...

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University ...

An effective treatment could be found for one of the most aggressive pediatric cancers, alveolar rhabdomyosarcoma (aRMS). These kinds of tumors, which develop mainly in skeletal muscle, are ...

Please provide your email address to receive an email when new articles are posted on . Patients with advanced chronic kidney disease may benefit from use of angiotensin-converting enzyme inhibitors ...

Researchers at the University of Illinois Chicago have found a small molecule capable of manipulating an immune process that plays an important role in cancers and autoimmune diseases. Their discovery ...

Renin–angiotensin system (RAS) inhibitors — including angiotensin-converting–enzyme (ACE) inhibitors and angiotensin-receptor blockers (ARBs) — slow the progression of mild or moderate chronic kidney ...

Lymphomas belong to the group of malignant diseases of the immune system and mainly affect the organs of the lymphatic system. Anaplastic large cell lymphoma (ALCL) belongs to the subgroup of ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...

From the 1950s to 1970s, discovery of enzymes began by identifying new chemical reactions within cell-free extracts, but ...