Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole ...

Cell-free protein synthesis (CFPS) represents a transformative technology in which the molecular machinery of transcription and translation is extracted from living cells and employed in a controlled ...

Under stress, animal cells pair inactive ribosomes into RNA-linked disomes. A ribosomal RNA “kissing loop” joins them, protecting ribosomes and reducing protein synthesis to conserve energy.<br /> ...

The yeast Kluyveromyces lactis (K. lactis) could become a highly productive, sustainable, cost-effective energy source for cell-free protein synthesis (CFPS) as biopharmaceutical manufacturers strive ...

Proteins are often called the building blocks of cells, but even those building blocks need to be built. One of the most important steps in the process of building proteins is glycosylation, when ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Ribosomes, the cell's protein-making factories, consume large amounts of energy as they build the proteins that keep cells alive and functioning. When cells experience stress—such as lack of nutrients ...

For much of modern biology, scientists argued that viruses are not alive, pointing to a basic limitation: they cannot make ...

Polyamines—natural molecules found in every living cell—have become stars in the longevity world for their ability to boost cellular cleanup and support healthy aging. But there’s a dark twist: high ...