Use of anxiolytic or hypnotic medications may significantly increase mortality risk, new research suggests. A retrospective cohort study of more than 100,000 age- and sex-matched patients showed that ...

Several lines of evidence indicate that inhibition of the metabotropic glutamate (mGlu) receptor 5 produces anxiolytic-like effects in rodents. Peptide neurotransmitter neuropeptide Y (NPY) produces ...

Objective: The primary aim of this study was to evaluate the psychomotor effects of mexazolam versus placebo in patients with generalised anxiety disorder (GAD). Patients and methods: This was a ...

Quick-acting targeted therapies with minimal side effects are an urgent need for the treatment of anxiety-related disorders. While delta opioid receptor (DOP) agonists have shown 'anxiolytic' or ...

Sedative-, hypnotic-, or anxiolytic- (SHA-) related disorders include SHA intoxication, SHA withdrawal, and SHA-use disorder. These disorders result from abuse of a class of medications known as ...

Objective To test the hypothesis that people taking anxiolytic and hypnotic drugs are at increased risk of premature mortality, using primary care prescription records and after adjusting for a wide ...

U.S. cancer survivors are significantly more likely to take medications for depression and anxiety compared with noncancer survivors, according to a study published online Aug. 19 in JAMA Network Open ...

Proprietary assays demonstrate dual Gq and β-arrestin signaling at 5-HT₂A, pathways linked in peer-reviewed studies to ...

Around ten percent of the population suffer from anxiety disorders, and current treatment options only offer effective help for a proportion of those affected. One of the changes observed in the ...

Sedative-, hypnotic-, or anxiolytic- (SHA-) related disorders include SHA intoxication, SHA withdrawal, and SHA-use disorder. These disorders result from abuse of a class of medications known as ...